Multiple antibiotic resistance has now become a major obstacle to the treatment of infectious diseases.In this context, the application of nanotechnology in medicine is a promising alternative for the prevention of infections with multidrug-resistant germs.The use of silver as a powerful antibacterial agent has attracted much interest.TiO2 and SiO2 thin films enhanced with Ag particles have been developed with the Electrotherapy and Sonic Therapy - Electrotherapy Electrodes aim of maintaining the transparency of the polymer films.Antibacterial activity was evaluated for a Gram-negative species-Escherichia coli-in concentrations of 105 and 104 CFU/mL in different conditions-activation by UV irradiation, single layer and double layer.
Increased antibacterial efficacy of TiO2-deposited foil was found for the tests that had been exposed to UV activation.In the case of bilayer tests, the efficiency was higher compared to those in a single layer, as the contact surface between the films and the bacterial suspension increased.Films can be used as a potential method to limit Oral Irrigators bacterial growth on hospital surfaces, such as telephone screens and medical equipment, given their optimized characteristics and proven antibacterial efficacy.